Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.63 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.61 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CKS1B | P61024 | 1/20 | 0.49 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3022618 | 0.92 | CYP4A11 (0.58) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL2294619 | 0.87 | CYP4A11 (0.52) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL2653681 | 0.85 | CYP4A11 (0.61) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL8235320 | 0.84 | CYP4A11 (0.49) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL8293519 | 0.83 | CYP4A11 (0.62) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL6656906 | 0.83 | CYP4A11 (0.62) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL2294490 | 0.83 | CYP4A11 (0.48) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL2291702 | 0.83 | CYP4A11 (0.48) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL70185 | 0.82 | CYP4A11 (0.75) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL31753280 | 0.81 | CYP4A11 (0.60) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142495-B1 | SUBSTITUTED DIBENZOIC ACID DERIVATIVES AND USE THEREOF | BAYER IP GMBH (DE) | 2016-04-27 | — | — | EP | disclosed |
| US-8217063-B2 | Lactam-substituted dicarboxylic acids and use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-07-10 | — | — | US | disclosed |
| US-8217063-B2 | Lactam-substituted dicarboxylic acids and use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-07-10 | — | — | US | disclosed |
| US-8217063-B2 | Lactam-substituted dicarboxylic acids and use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-07-10 | — | — | US | disclosed |
| US-7985876-B2 | Substituted dibenzoic acid derivatives and use thereof | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-07-26 | — | — | US | disclosed |
| US-7985876-B2 | Substituted dibenzoic acid derivatives and use thereof | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-07-26 | — | — | US | disclosed |
| US-7985876-B2 | Substituted dibenzoic acid derivatives and use thereof | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-07-26 | — | — | US | disclosed |
| US-20100197680-A1 | LACTAM-SUBSTITUTED DICARBOXYLIC ACIDS AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2010-08-05 | — | — | US | disclosed |
| US-20100197680-A1 | LACTAM-SUBSTITUTED DICARBOXYLIC ACIDS AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2010-08-05 | — | — | US | disclosed |
| US-20100197680-A1 | LACTAM-SUBSTITUTED DICARBOXYLIC ACIDS AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2010-08-05 | — | — | US | disclosed |
| US-20100168240-A1 | SUBSTITUTED DIBENZOIC ACID DERIVATIVES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-07-01 | — | — | US | disclosed |
| US-20100168240-A1 | SUBSTITUTED DIBENZOIC ACID DERIVATIVES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-07-01 | — | — | US | disclosed |
| US-20100168240-A1 | SUBSTITUTED DIBENZOIC ACID DERIVATIVES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-07-01 | — | — | US | disclosed |
| WO-2008119457-A2 | LACTAM-SUBSTITUTED DICARBOXYLIC ACIDS AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008119458-A1 | SUBSTITUTED DIBENZOIC ACID DERIVATIVES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168240-A1 | SUBSTITUTED DIBENZOIC ACID DERIVATIVES AND USE THEREOF | BBOX1, DDC, DDT | CYP4A11 158/4885CYP4F2 76/4885LOXL2 2634/4885 |
| US-20100197680-A1 | LACTAM-SUBSTITUTED DICARBOXYLIC ACIDS AND USE THEREOF | DDO, DDC, BCAT2 | CYP4A11 2160/4885CYP4F2 672/4885LOXL2 1834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.