Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAP3K7 | O43318 | 4/20 | 0.34 |
| ▸ | TAB1 | Q15750 | 4/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25469864 | 0.70 | MEN1 (0.35) | MEN1LMNAPOLBHTTKMT2A | |
| SCHEMBL25807400 | 0.68 | MEN1 (0.38) | MEN1LMNAPOLBHTTKMT2A | |
| SCHEMBL17248008 | 0.67 | NOS3 (0.41) | MEN1LMNAPOLBHTTKMT2A | |
| SCHEMBL19121798 | 0.67 | MEN1 (0.49) | MEN1LMNAPOLBHTTKMT2A | |
| SCHEMBL17648154 | 0.65 | MAP3K7 (0.39) | MEN1LMNAPOLBHTTKMT2A | |
| SCHEMBL22595114 | 0.65 | CNR2 (0.38) | MEN1LMNAKMT2AL3MBTL1 | |
| SCHEMBL20361824 | 0.65 | XDH (0.36) | MEN1LMNAPOLBHTTKMT2A | |
| SCHEMBL18049863 | 0.65 | NUDT1 (0.60) | MEN1LMNAPOLBHTTKMT2A | |
| SCHEMBL14472116 | 0.64 | ALDH1A1 (0.44) | MEN1POLBKMT2ASMN1; SMN2PRKD3 | |
| SCHEMBL10735673 | 0.63 | MEN1 (0.39) | MEN1LMNAPOLBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243303-A1 | PYRIDINYL AND PYRAZINYL-(AZA)INDOLSULFONAMIDES | UCB PHARMA GMBH (DE) | 2019-12-26 | — | — | WO | disclosed |