Water

Water

SCHEMBL216104

O.O.O.O.O.O=[N+]([O-])[O-].[BiH3]

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 known ✓ O00255 1/20 0.67
KMT2A Q03164 1/20 0.67
CA5A P35218 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
TSHR P16473 3/20 0.39
ALDH1A1 P00352 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
HPGD P15428 1/20 0.36
HIF1A Q16665 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL1362222 1.00
Water SCHEMBL3794611 1.00 MEN1 (0.67) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL28774538 0.94 MEN1 (0.60) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL28398822 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL2590832 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL28478211 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL708617 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL10566608 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
SCHEMBL3720575 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL10896609 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6363 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122076476-A Yb-BiOI/Ce-MgAl-LDH composite photocatalyst and preparation method and application thereof 2026-05-26 CN claimed
CN-122076460-A Metal doped bismuth ferrite based perovskite composite material and preparation method and application thereof 2026-05-26 CN claimed
CN-116426966-B Cobalt oxide nanoparticle loaded bismuth sodium titanate piezoelectric catalyst and preparation method and application thereof QINGDAO UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2026-05-26 CN claimed
CN-122080778-A Lamp with self-cleaning light response function coating and preparation method thereof 2026-05-26 CN claimed
CN-122076421-A Method for in-situ synthesis of visible light photocatalytic polymer by utilizing vanadium-containing solid waste 2026-05-26 CN claimed
CN-122075686-A Bismuth-copper bimetallic coordination nano material and preparation method and application thereof 2026-05-26 CN claimed
CN-122082033-A Composite photoelectrode for preparing ketone compound from photoelectrocatalytic polyol, preparation method and application 2026-05-26 CN claimed
CN-122080923-A Preparation method and application of indium sulfide/bismuth sulfide heterojunction bionic micron dendrite broadband photoelectric detection material 2026-05-26 CN claimed
CN-121896025-B Bismuth-based metal passivator and preparation method thereof JIANGSU CHUANGXIN PETROCHEMICAL Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122076473-A Sheet-shaped p-n heterojunction BiOBr/CoWO4Visible light catalytic material and preparation method and application thereof 2026-05-26 CN claimed
WO-2014097316-A2 X-RAY SHIELDING MATERIAL AND METHOD OF PREPARATION THEREOF Centre for Materials for Electronics Technology (C-MET) (IN) 2014-06-26 WO claimed
EP-2717934-A1 BISMUTH PARTICLE X-RAY CONTRAST AGENTS The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Portland State University (US) 2014-04-16 EP claimed
WO-2012170569-A1 BISMUTH PARTICLE X-RAY CONTRAST AGENTS STATE OF OREGON BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY (US) 2012-12-13 WO claimed
US-8058195-B2 Nanoglass and flame spray processes for producing nanoglass CABOT CORPORATION (US) 2011-11-15 US claimed
WO-2010119448-A1 AN 'IN-SITU' PREPARED, IMPROVED CATALYST FOR LOW PRESSURE CONTINUOUS BUTYNEDIOL SYNTHESIS HINDUSTAN ORGANIC CHEMICALS LIMITED (IN) 2010-10-21 WO claimed
US-20080318757-A1 NANOGLASS AND FLAME SPRAY PROCESSES FOR PRODUCING NANOGLASS CABOT CORPORATION (US) 2008-12-25 US claimed
WO-2008157719-A1 NANOGLASS AND FLAME SPRAY PROCESSES FOR PRODUCING NANOGLASS CABOT CORPORATION (US) 2008-12-24 WO claimed
US-20050258404-A1 Bismuth compounds composite MCCORD STUART J 2005-11-24 US claimed
US-6187165-B1 Arrays of semi-metallic bismuth nanowires and fabrication techniques therefor THE JOHN HOPKINS UNIVERSITY 2001-02-13 US claimed
US-4052332-A CATALYST REGENERATION WITH IMPREGNATION OF BISMUTH AND MOLYBDENUM E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-10-04 US claimed