Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 9/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.35 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23321023 | 0.86 | BACE1 (0.31) | PIM1 | |
| SCHEMBL28339887 | 0.81 | PIM1 (0.51) | PIM1PIM2LMNATP53CSNK2A1 | |
| SCHEMBL15518178 | 0.72 | LIPG (0.40) | — | |
| SCHEMBL21612887 | 0.71 | P4HB (0.49) | THRBMAPK1KDM4E | |
| SCHEMBL21612866 | 0.71 | CA9 (0.36) | LMNATP53ALDH1A1MAPK1HPGD | |
| SCHEMBL23801191 | 0.70 | HIF1A (0.41) | ALDH1A1TSHRHPGDHSD17B10KDM4E | |
| SCHEMBL21612932 | 0.70 | PRKACA (0.33) | TSHRMAPK1 | |
| SCHEMBL15518375 | 0.69 | LPL (0.40) | — | |
| SCHEMBL2960924 | 0.69 | NPC1 (0.56) | ALDH1A1TSHRMAPK1HPGDSMN1; SMN2 | |
| SCHEMBL21612867 | 0.69 | CA1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020009176-A1 | AMIDE COMPOUND HAVING BET PROTEOLYSIS-INDUCING ACTION AND MEDICINAL APPLICATION THEREOF | 田辺三菱製薬株式会社 | 2020-01-09 | — | — | WO | disclosed |