SCHEMBL23801191

SCHEMBL23801191

CC1(C)CCCCOB(c2ccc(OCC(=O)O)cc2)OC1(C)C

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 5/20 0.41
SMN1; SMN2 Q16637 1/20 0.37
ALOX15 P16050 2/20 0.36
ALDH1A1 P00352 3/20 0.36
HSD17B10 Q99714 2/20 0.36
KDM4E B2RXH2 1/20 0.36
GLA P06280 1/20 0.36
GAA P10253 1/20 0.36
HPGD P15428 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
AAK1 Q2M2I8 1/20 0.35
TSHR P16473 2/20 0.35
NR4A1 P22736 1/20 0.35
APEX1 P27695 1/20 0.35
FFAR1 O14842 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30188658 0.86 AAK1 (0.43) HIF1AAAK1
SCHEMBL21612866 0.82 CA9 (0.36) ALDH1A1HSD17B10KDM4EGLAGAA
SCHEMBL23321264 0.81 PTGDR2 (0.38) HIF1AALDH1A1HSD17B10KDM4EHPGD
SCHEMBL21612867 0.81 CA1 (0.35) AAK1
SCHEMBL1572955 0.80 HIF1A (0.56) HIF1ASMN1; SMN2ALOX15ALDH1A1AAK1
SCHEMBL15518178 0.77 LIPG (0.40)
SCHEMBL21612887 0.76 P4HB (0.49) KDM4EFFAR1
SCHEMBL15518375 0.74 LPL (0.40)
SCHEMBL23320752 0.72 FFAR1 (0.42) FFAR1
SCHEMBL30188573 0.71 P4HB (0.42) AAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11542273-B2 Amide compound having bet proteolysis-inducing action and medicinal application thereof MITSUBISHI TANABE PHARMA CORPORATION (JP) 2023-01-03 US disclosed
US-20210284654-A1 AMIDE COMPOUND HAVING BET PROTEOLYSIS-INDUCING ACTION AND MEDICINAL APPLICATION THEREOF MITSUBISHI TANABE PHARMA CORPORATION (JP) 2021-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11542273-B2 Amide compound having bet proteolysis-inducing action and medicinal application thereof BET1, BRD4, PHKB HIF1A 1923/4885SMN1; SMN2 4500/4885ALOX15 4005/4885
US-20210284654-A1 AMIDE COMPOUND HAVING BET PROTEOLYSIS-INDUCING ACTION AND MEDICINAL APPLICATION THEREOF BET1, BRD4, PHKB HIF1A 1879/4885SMN1; SMN2 4459/4885ALOX15 4043/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.