Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | ASPH | Q12797 | 5/20 | 0.36 |
| ▸ | KDM8 | Q8N371 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | RIOX2 | Q8IUF8 | 2/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30340445 | 0.87 | SIRT6 (0.41) | HCAR2PRKCELMNASIRT6 | |
| SCHEMBL28476138 | 0.87 | MAPK1 (0.41) | HCAR2L3MBTL1POLBKDM4EMAPK1 | |
| SCHEMBL21616774 | 0.76 | GPR35 (0.43) | P4HTML3MBTL1KDM4EASPHKDM8 | |
| SCHEMBL21616724 | 0.76 | KMO (0.40) | P4HTML3MBTL1KDM4EASPHKDM8 | |
| SCHEMBL30340453 | 0.76 | GPR35 (0.43) | P4HTML3MBTL1KDM4EASPHKDM8 | |
| SCHEMBL28986848 | 0.76 | LMNA (0.39) | L3MBTL1TDP1POLBKDM4EPRKCE | |
| SCHEMBL28666415 | 0.72 | CD274 (0.38) | HCAR2L3MBTL1TDP1KDM4EASPH | |
| SCHEMBL24660110 | 0.72 | ASPH (0.40) | HCAR2L3MBTL1TDP1KDM4EASPH | |
| SCHEMBL11027593 | 0.67 | HCAR2 (0.46) | HCAR2P4HTML3MBTL1TDP1POLB | |
| SCHEMBL2631698 | 0.66 | P4HTM (0.61) | HCAR2P4HTML3MBTL1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020011209-A1 | IMMUNOSUPPRESSIVE AGENT, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 上海和誉生物医药科技有限公司 | 2020-01-16 | — | — | WO | disclosed |