Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 19/20 | 0.45 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21619714 | 0.92 | RORC (0.43) | RORC | |
| SCHEMBL21619715 | 0.85 | RORC (0.47) | RORC | |
| SCHEMBL21619696 | 0.85 | RORC (0.51) | RORC | |
| SCHEMBL21619742 | 0.84 | RORC (0.43) | RORC | |
| SCHEMBL21619697 | 0.83 | RORC (0.50) | RORC | |
| SCHEMBL21616635 | 0.81 | RORC (0.44) | RORC | |
| SCHEMBL21616619 | 0.80 | RORC (0.44) | RORC | |
| SCHEMBL28525983 | 0.80 | RORC (0.44) | RORC | |
| SCHEMBL23636960 | 0.79 | MCHR1 (0.48) | RORC | |
| SCHEMBL28600987 | 0.79 | MCHR1 (0.48) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020011147-A1 | RORγ ANTAGONIST AND APPLICATION THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-01-16 | — | — | WO | disclosed |