Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPC | P11150 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21616633 | 0.86 | LIPC (0.40) | LIPCLIPGTSHRNOD2NOD1 | |
| SCHEMBL21620204 | 0.85 | FPR1 (0.34) | FPR1FPR2KDM1ARCOR1HTR2C | |
| SCHEMBL28535402 | 0.85 | HSD11B1 (0.38) | HTR2C | |
| SCHEMBL28532617 | 0.78 | LIPC (0.40) | LIPCLIPGALDH1A1POLBTSHR | |
| SCHEMBL30474464 | 0.78 | KDM1A (0.35) | DRD2DRD4FPR1FPR2KDM1A | |
| SCHEMBL28526782 | 0.77 | CYP3A4 (0.44) | FPR1FPR2ALDH1A1POLBTSHR | |
| SCHEMBL23632088 | 0.77 | P2RY14 (0.38) | LIPGFPR1FPR2CCR2 | |
| SCHEMBL21616645 | 0.77 | P2RY14 (0.38) | LIPGFPR1FPR2CCR2 | |
| SCHEMBL28614536 | 0.77 | P2RY14 (0.38) | LIPGFPR1FPR2CCR2 | |
| SCHEMBL28626815 | 0.77 | P2RY14 (0.38) | LIPGFPR1FPR2CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020011147-A1 | RORγ ANTAGONIST AND APPLICATION THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-01-16 | — | — | WO | disclosed |