Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14689801 | 0.82 | HSD17B10 (0.51) | NOTUMSMN1; SMN2ALDH1A1HSD17B10KDM4E | |
| SCHEMBL12093606 | 0.81 | ADRB1 (0.53) | SMN1; SMN2ALDH1A1TSHRGAALMNA | |
| SCHEMBL1057318 | 0.81 | ADRB1 (0.50) | NOTUMSMN1; SMN2ALDH1A1HSD17B10KDM4E | |
| SCHEMBL5460658 | 0.80 | GAA (0.62) | NOTUMSMN1; SMN2ALDH1A1HSD17B10KDM4E | |
| SCHEMBL23368563 | 0.79 | GAA (0.67) | ALDH1A1HSD17B10KDM4EPOLBGAA | |
| SCHEMBL15676577 | 0.78 | NOTUM (0.42) | NOTUMSMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL30149942 | 0.78 | NOTUM (0.42) | NOTUMSMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL28382978 | 0.78 | NOTUM (0.38) | NOTUMSMN1; SMN2ALDH1A1HSD17B10KDM4E | |
| SCHEMBL14566099 | 0.77 | NOTUM (0.57) | NOTUMSMN1; SMN2ALDH1A1HSD17B10KDM4E | |
| SCHEMBL377688 | 0.77 | NOTUM (0.53) | NOTUMSMN1; SMN2ALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 990 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116606338-A | 6' -cyano modified locked nucleosides, nucleotides and nucleic acid polymers | 中国人民解放军军事科学院军事医学研究院 | 2023-08-18 | — | — | CN | claimed |
| US-20230192751-A1 | METHOD FOR THE PREPARATION OF OLIGONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) | 2023-06-22 | — | — | US | claimed |
| EP-3119789-B1 | BICYCLIC CARBOCYCLIC NUCLEOSIDES AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM | IONIS PHARMACEUTICALS INC (US) | 2020-04-22 | — | — | EP | claimed |
| US-10287313-B2 | RNA monomers containing 0-acetal levulinyl ester groups and their use in RNA microarrays | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2019-05-14 | — | — | US | claimed |
| EP-3323414-A1 | INHIBITORS OF NEDD8-ACTIVATING ENZYME | Millennium Pharmaceuticals, Inc. (US) | 2018-05-23 | — | — | EP | claimed |
| EP-2850092-B1 | TRICYCLIC NUCLEIC ACID ANALOGS | IONIS PHARMACEUTICALS INC (US) | 2017-03-01 | — | — | EP | claimed |
| US-20160340382-A1 | RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2016-11-24 | — | — | US | claimed |
| EP-2727915-B1 | Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof | CONCERT PHARMACEUTICALS INC (US) | 2016-04-13 | — | — | EP | claimed |
| EP-2334692-B1 | RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS | UNIV MCGILL (CA) | 2016-04-13 | — | — | EP | claimed |
| EP-2580228-B1 | SUBSTITUTED 2'-AMINO AND 2'-THIO-BICYCLIC NUCLEOSIDES AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM | IONIS PHARMACEUTICALS INC (US) | 2016-03-23 | — | — | EP | claimed |
| US-20060173199-A1 | Method of preparation of heterocyclic molecules with pharmaceutical, pharmaceutical excipient, cosmeceutical, agrochemical and industrial uses | HONG BORCHERNG | 2006-08-03 | — | — | US | claimed |
| EP-1594835-A2 | METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES | Auspex Pharmaceuticals, Inc. (US) | 2005-11-16 | — | — | EP | claimed |
| EP-1589028-A2 | Modified oligonucleotides, their preparation and their use | Aventis Pharma Deutschland GmbH (DE) | 2005-10-26 | — | — | EP | claimed |
| WO-2004064745-A2 | METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES | AUSPEX PHARMACEUTICALS, INC. (US) | 2004-08-05 | — | — | WO | claimed |
| US-5789562-A | STABLE HYBRIDIZATION COMPLEXES WITH NUCLEI ACIDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | claimed |
| US-5721350-A | Deuterated nucleosides | CHATTOPADHYAYA JYOTI (SE) | 1998-02-24 | — | — | US | claimed |
| EP-0710667-A2 | Modified oligonucleotides, their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-05-08 | — | — | EP | claimed |
| EP-0680969-A2 | Modified oligonucleotides, their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-11-08 | — | — | EP | claimed |
| EP-0648220-A1 | DEUTERATED NUCLEOSIDES | CHATTOPADHYAYA, Jyoti (SE) | 1995-04-19 | — | — | EP | claimed |
| WO-1993025566-A1 | DEUTERATED NUCLEOSIDES | CHATTOPADHYAYA JYOTI (SE) | 1993-12-23 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10287313-B2 | RNA monomers containing 0-acetal levulinyl ester groups and their use in RNA microarrays | EFTUD2, RNMT, NSUN2 | NOTUM 1889/4885SMN1; SMN2 905/4885ALDH1A1 199/4885 |
| US-20160340382-A1 | RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS | EFTUD2, RNMT, RNGTT | NOTUM 2025/4885SMN1; SMN2 1087/4885ALDH1A1 212/4885 |
| US-20060173199-A1 | Method of preparation of heterocyclic molecules with pharmaceutical, pharmaceutical excipient, cosmeceutical, agrochemical and industrial uses | LSS, DHPS, CYP51A1 | NOTUM 256/4885SMN1; SMN2 4543/4885ALDH1A1 1435/4885 |
| US-20230192751-A1 | METHOD FOR THE PREPARATION OF OLIGONUCLEOTIDES | POLN, POLRMT, POLI | NOTUM 4122/4885SMN1; SMN2 1452/4885ALDH1A1 4284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.