SCHEMBL21628429

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628886	0.99	RARB (0.53)	RARBPLA2G4ARARARARGMEN1
	SCHEMBL21628425	0.95	RARB (0.48)	RARBPLA2G4ARARARARGMEN1
	SCHEMBL21628805	0.91	PTGER4 (0.46)	RARBALDH1A1NPC1RAB9ASMN1; SMN2
	SCHEMBL21628454	0.90	ICAM1 (0.49)	RARBPLA2G4ARARARARGMEN1
	SCHEMBL21628473	0.89	MAPT (0.49)	RARBPLA2G4ARARARARGMAPT
	SCHEMBL21628609	0.89	ICAM1 (0.48)	RARBPLA2G4ARARARARG
	SCHEMBL21628638	0.88	PLA2G4A (0.46)	RARBPLA2G4ARARARARG
	SCHEMBL21628698	0.88	PLK1 (0.48)	RARBPLA2G4ARARARARG
	SCHEMBL21628415	0.88	SMPD1 (0.53)	RARB
	SCHEMBL21628478	0.88	MAPT (0.50)	RARBRARARARGMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.