SCHEMBL21628478

SCHEMBL21628478

CCCCCc1ccc(Oc2ncc(C(=O)OC)cc2F)cc1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
MDH1 P40925 2/20 0.49
RARB P10826 3/20 0.43
CYP4A11 Q02928 2/20 0.43
CYP4F2 P78329 1/20 0.43
THRB P10828 1/20 0.41
PLK1 P53350 1/20 0.41
PLK3 Q9H4B4 1/20 0.41
RARA P10276 1/20 0.40
RARG P13631 1/20 0.40
SMPD1 P17405 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21628473 0.99 MAPT (0.49) MAPTSMN1; SMN2MDH1RARBCYP4A11
SCHEMBL21628713 0.97 MDH1 (0.48) MAPTSMN1; SMN2MDH1RARBCYP4A11
SCHEMBL21628424 0.92 VNN1 (0.42) MAPTSMN1; SMN2MDH1CYP4A11
SCHEMBL21628741 0.90 PLA2G4A (0.45) MAPTSMN1; SMN2MDH1RARBTHRB
SCHEMBL21628399 0.89 PLA2G4A (0.46) RARBTHRBRARARARG
SCHEMBL21628886 0.89 RARB (0.53) MAPTSMN1; SMN2RARBRARARARG
SCHEMBL21628482 0.88 VNN1 (0.44) MAPTSMN1; SMN2
SCHEMBL21628883 0.88 SMPD1 (0.52) RARBSMPD1
SCHEMBL21628857 0.88 PLK1 (0.49) MAPTSMN1; SMN2RARBPLK1PLK3
SCHEMBL29921175 0.88 PLK1 (0.49) MAPTSMN1; SMN2RARBPLK1PLK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600696-B2 Aromatic compounds Xeniopro GmbH (DE) 2026-04-14 US disclosed
US-20230406814-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2023-12-21 US disclosed
US-20230150923-A1 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2023-05-18 US disclosed
US-11591289-B2 Aromatic compounds Xeniopro GmbH (DE) 2023-02-28 US disclosed
US-11591289-B2 Aromatic compounds Xeniopro GmbH (DE) 2023-02-28 US disclosed
US-20220348535-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2022-11-03 US disclosed
US-20200031763-A1 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2020-01-30 US disclosed
US-20200031763-A1 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2020-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150923-A1 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK MAPT 2272/4885SMN1; SMN2 796/4885MDH1 1376/4885
US-20220348535-A2 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK MAPT 2272/4885SMN1; SMN2 796/4885MDH1 1376/4885
US-11591289-B2 Aromatic compounds AHR, TYR, MUSK MAPT 2195/4885SMN1; SMN2 1107/4885MDH1 1290/4885
US-12600696-B2 Aromatic compounds CCR1, CCRL2, AHR MAPT 4404/4885SMN1; SMN2 919/4885MDH1 2247/4885
US-20230406814-A2 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK MAPT 2272/4885SMN1; SMN2 796/4885MDH1 1376/4885
US-20200031763-A1 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK MAPT 2272/4885SMN1; SMN2 796/4885MDH1 1376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.