SCHEMBL21628805

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628425	0.93	RARB (0.48)	PTGER4PTGER2SMN1; SMN2RAB9ANPC1
	SCHEMBL21628886	0.92	RARB (0.53)	PTGER4SMN1; SMN2RAB9ANPC1RARB
	SCHEMBL21628429	0.91	RARB (0.55)	SMN1; SMN2RAB9ANPC1RARBALDH1A1
	SCHEMBL21628506	0.90	RXRA (0.49)	PTGER4PTGER2SMN1; SMN2RAB9ANPC1
	SCHEMBL21628512	0.89	OPRM1 (0.43)	PTGER4RAB9ASENP8SENP7SENP6
	SCHEMBL21628424	0.88	VNN1 (0.42)	PTGER4SMN1; SMN2RAB9ANPC1SENP8
	SCHEMBL21628761	0.87	MAOB (0.46)	PTGER4SENP8SENP7SENP6P2RX3
	SCHEMBL21628586	0.87	ALDH1A1 (0.41)	PTGER4SMN1; SMN2RAB9ANPC1SENP8
	SCHEMBL21628686	0.87	PLK1 (0.51)	PTGER4PTGER2SMN1; SMN2RAB9ASENP8
	SCHEMBL21628856	0.87	PTGER4 (0.44)	PTGER4PTGER2RAB9ASENP8SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.