SCHEMBL21628696

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628794	0.90	PLK1 (0.58)	PLK1SLC6A2SLC6A4HPGDTSHR
	SCHEMBL21628403	0.90	OPRM1 (0.52)	TAS1R3TAS1R1OPRM1OPRK1
	SCHEMBL21628775	0.88	PLK1 (0.60)	PLK1SLC6A2SLC6A4HPGDTSHR
	SCHEMBL21628799	0.87	PLK1 (0.56)	PLK1SLC6A2SLC6A4
	SCHEMBL21628662	0.86	KMT2A (0.48)	HPGDHTTSMN1; SMN2
	SCHEMBL21628910	0.86	PLK1 (0.54)	PLK1
	SCHEMBL21656765	0.85	MMP13 (0.65)	PLK1SLC6A2SLC6A4HPGDTSHR
	SCHEMBL21628551	0.85	LMNA (0.56)	HTT
	SCHEMBL21628562	0.84	PARP10 (0.55)	SLC6A2SLC6A4OPRM1OPRK1
	SCHEMBL21628653	0.83	CA12 (0.47)	OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.