SCHEMBL21628706

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20827025	0.91	MAOB (0.47)	MAOBPOLBCYP2C9NPC1RAB9A
	SCHEMBL20482112	0.90	NPC1 (0.46)	POLBCYP2C9NPC1RAB9ATDP1
	SCHEMBL21628567	0.89	MAOB (0.57)	MAOBPOLBCYP2C9NPC1RAB9A
	SCHEMBL20482495	0.87	NPC1 (0.56)	POLBCYP2C9NPC1RAB9ATDP1
	SCHEMBL21628678	0.87	MAOB (0.50)	MAOBPOLBCYP2C9CYP1A2CYP2C19
	SCHEMBL21628397	0.87	MAOB (0.48)	MAOBPOLBCYP2C9CYP1A2CYP2C19
	SCHEMBL21628378	0.86	NPC1 (0.46)	MAOBPOLBCYP2C9NPC1RAB9A
	SCHEMBL21628659	0.86	MAOB (0.52)	MAOBPOLBCYP2C9CYP1A2CYP2C19
	SCHEMBL21628642	0.85	MAOB (0.48)	MAOBPOLBCYP2C9RAB9ACYP1A2
	SCHEMBL21628414	0.84	NPC1 (0.45)	POLBCYP2C9NPC1RAB9ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.