SCHEMBL21628402

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21657001	0.90	OPRM1 (0.55)	HDAC6HDAC8GRNSORT1OPRM1
	SCHEMBL21656683	0.86	LMNA (0.55)	HDAC6HDAC8GRNSORT1OPRM1
	SCHEMBL21628390	0.86	OPRM1 (0.48)	HDAC6HDAC8GRNSORT1OPRM1
	SCHEMBL21656515	0.86	MAPT (0.56)	HDAC6HDAC8GRNSORT1OPRM1
	SCHEMBL21656612	0.85	OPRM1 (0.56)	OPRM1OPRD1OPRK1
	SCHEMBL21628751	0.84	HDAC6 (0.81)	HDAC6HDAC8HDAC1HDAC3HDAC4
	SCHEMBL21628734	0.83	OPRM1 (0.54)	HDAC6HDAC8GRNSORT1OPRM1
	SCHEMBL21656691	0.82	PDE4B (0.53)	HDAC6HDAC8OPRM1OPRD1OPRK1
	SCHEMBL21628757	0.82	ALDH1A1 (0.48)	HDAC6HDAC8GRNSORT1OPRM1
	SCHEMBL21628756	0.81	POLB (0.59)	HDAC6HDAC8GRNSORT1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.