SCHEMBL21628773

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628807	0.89	PARP10 (0.54)	PARP10CHEK2SLC6A2SLC6A4OPRK1
	SCHEMBL21628754	0.89	PARP10 (0.56)	PARP10CHEK2SLC6A2SLC6A4OPRK1
	SCHEMBL21628817	0.88	LMNA (0.51)	PARP10IGFBP3KDM4EMAPT
	SCHEMBL21628736	0.87	PARP10 (0.51)	PARP10CHEK2SLC6A2SLC6A4OPRK1
	SCHEMBL21628387	0.86	PARP10 (0.50)	PARP10CHEK2SLC6A2SLC6A4OPRK1
	SCHEMBL21628485	0.85	PARP10 (0.55)	PARP10CHEK2SLC6A2SLC6A4OPRK1
	SCHEMBL21628726	0.84	OPRM1 (0.45)	OPRK1OPRM1IGFBP3KDM4EMAPT
	SCHEMBL21628850	0.84	ALDH1A1 (0.51)	SLC6A2SLC6A4ALDH1A1KMT2AIGFBP3
	SCHEMBL21628898	0.83	SLC6A2 (0.53)	PARP10SLC6A2SLC6A4ALDH1A1KMT2A
	SCHEMBL3024115	0.83	PARP10 (0.67)	PARP10CHEK2SLC6A2SLC6A4OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.