SCHEMBL21628821

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628553	0.90	OPRM1 (0.54)	LMNAGRNSORT1LIPEOPRM1
	SCHEMBL21656684	0.86	LMNA (0.64)	LMNAGRNSORT1LIPERAB9A
	SCHEMBL19362859	0.86	RAB9A (0.57)	LMNAGRNSORT1LIPERAB9A
	SCHEMBL21628465	0.86	NPC1 (0.58)	RAB9ANPC1POLBCYP2C9MAPT
	SCHEMBL21628591	0.85	OPRM1 (0.55)	LMNARAB9ANPC1POLBCYP2C9
	SCHEMBL19363006	0.83	PDE4B (0.53)	LMNAGRNSORT1LIPERAB9A
	SCHEMBL21628717	0.83	LMNA (0.47)	LMNAGRNSORT1LIPERAB9A
	SCHEMBL21628734	0.82	OPRM1 (0.54)	LMNAGRNSORT1LIPEPOLB
	SCHEMBL20482700	0.82	LMNA (0.64)	LMNALIPERAB9ANPC1HDAC1
	SCHEMBL21656866	0.82	LMNA (0.45)	LMNAGRNSORT1LIPEPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.