SCHEMBL21628872

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628618	0.95	ALDH1A1 (0.65)	ALDH1A1HPGDSMN1; SMN2RARBTHRA
	SCHEMBL21628779	0.94	ALDH1A1 (0.63)	ALDH1A1HPGDSMN1; SMN2RARBTHRA
	SCHEMBL21628655	0.91	ALDH1A1 (0.71)	ALDH1A1HPGDSMN1; SMN2PLK1THRB
	SCHEMBL26148083	0.91	RARB (0.59)	ALDH1A1HPGDRARBPLK1THRA
	SCHEMBL21628697	0.84	OPRM1 (0.50)	ALDH1A1HPGDSMN1; SMN2PLA2G4A
	SCHEMBL21628616	0.84	ALDH1A1 (0.76)	ALDH1A1HPGDSMN1; SMN2PLK1
	SCHEMBL21628432	0.83	LPAR1 (0.51)	ALDH1A1HPGDSMN1; SMN2RARBTHRA
	SCHEMBL21656831	0.83	RARB (0.73)	ALDH1A1HPGDRARBPLK1THRA
	SCHEMBL30663616	0.82	ALDH1A1 (0.49)	ALDH1A1HPGDSMN1; SMN2RARBPLK1
	SCHEMBL21628604	0.81	PARP10 (0.61)	ALDH1A1SMN1; SMN2RARBPLK1THRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.