Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25740924 | 0.80 | SLC6A3 (0.57) | CARM1PRMT6SLC6A3BCHEACHE | |
| SCHEMBL5870682 | 0.76 | OPRD1 (0.62) | SLC6A3ACHE | |
| SCHEMBL5870685 | 0.76 | OPRD1 (0.62) | SLC6A3ACHE | |
| SCHEMBL5870753 | 0.76 | OPRD1 (0.62) | SLC6A3ACHE | |
| SCHEMBL4839281 | 0.76 | OPRM1 (0.58) | KMT2ASLC6A3 | |
| SCHEMBL7248339 | 0.76 | CARM1 (0.70) | CARM1PRMT6SLC6A3BCHE | |
| Bromide SCHEMBL7247812 | 0.74 | CARM1 (0.68) | CARM1PRMT6SLC6A3BCHE | |
| SCHEMBL6498997 | 0.74 | LTA4H (0.48) | KMT2ASLC6A3LTA4HEPHX2 | |
| SCHEMBL14947440 | 0.74 | CARM1 (0.64) | CARM1PRMT6SLC6A3BCHEACHE | |
| SCHEMBL5870834 | 0.73 | OPRM1 (0.55) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020016315-A1 | FUSED DIHYDROINDAZOLE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2020-01-23 | — | — | WO | disclosed |