Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 6/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23611631 | 0.81 | FFAR2 (0.43) | FFAR2 | |
| SCHEMBL12533357 | 0.81 | MAOB (0.39) | NOTUMCREBBPFFAR2MAOBSMN1; SMN2 | |
| SCHEMBL18711628 | 0.76 | SPR (0.44) | NOTUMCREBBPPOLBMAOB | |
| SCHEMBL13116614 | 0.75 | TERT (0.46) | FFAR2 | |
| SCHEMBL13137753 | 0.74 | GPR119 (0.47) | PKM | |
| SCHEMBL10856406 | 0.74 | NOTUM (0.43) | NOTUMCREBBPPOLBSMN1; SMN2 | |
| SCHEMBL24102467 | 0.74 | FFAR2 (0.55) | FFAR2 | |
| SCHEMBL24102463 | 0.74 | FFAR2 (0.55) | FFAR2 | |
| SCHEMBL23611546 | 0.73 | CYP3A4 (0.46) | FFAR2SMN1; SMN2 | |
| SCHEMBL23611571 | 0.73 | CYP3A4 (0.46) | FFAR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020018434-A1 | COMPOSITIONS AND METHODS FOR DISRUPTING A MACROPHAGE NETWORK | SCRIPPS HEALTH (US) | 2020-01-23 | — | — | WO | disclosed |