Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5281093 | 0.75 | CA2 (0.61) | CA12CA1CA2CA9ASIC3 | |
| SCHEMBL7190905 | 0.75 | PTGS2 (0.45) | CA12CA1CA2CA9ASIC3 | |
| SCHEMBL5808117 | 0.71 | CYP1A2 (0.54) | ASIC3KMT2AL3MBTL1LMNA | |
| SCHEMBL21647723 | 0.70 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1KMT2AL3MBTL1APOBEC3G | |
| SCHEMBL21647731 | 0.70 | MEN1 (0.43) | CA2MEN1KMT2AL3MBTL1APOBEC3G | |
| SCHEMBL4014559 | 0.70 | LMNA (0.41) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL11576079 | 0.69 | APOBEC3G (0.56) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL46622 | 0.68 | ASIC3 (0.48) | CA12CA1CA2CA9ASIC3 | |
| SCHEMBL8973992 | 0.68 | ALDH1A1 (0.57) | CA1CA2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL16550139 | 0.67 | KMT2A (0.59) | CA12CA1CA2CA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513011-B | Benzene derivatives | 小野药品工业株式会社 | 2023-06-16 | — | — | CN | disclosed |
| CN-112513011-A | Benzene derivatives | 小野药品工业株式会社 | 2021-03-16 | — | — | CN | disclosed |
| WO-2020027150-A1 | BENZENE DERIVATIVE | 小野薬品工業株式会社 | 2020-02-06 | — | — | WO | disclosed |