Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 6/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21648543 | 1.00 | MAPKAPK2 (0.47) | MAPKAPK2SIRT1MAPTALDH1A1HTR2B | |
| SCHEMBL21648557 | 0.87 | CHRNA7 (0.44) | MAPTALDH1A1HTR2BKDM4EHPGD | |
| SCHEMBL21648556 | 0.87 | CHRNA7 (0.44) | MAPTALDH1A1HTR2BKDM4EHPGD | |
| SCHEMBL21648506 | 0.82 | MAPKAPK2 (0.46) | MAPKAPK2SIRT1MAPTALDH1A1HTR2B | |
| SCHEMBL21648504 | 0.82 | MAPKAPK2 (0.46) | MAPKAPK2SIRT1MAPTALDH1A1HTR2B | |
| SCHEMBL8039623 | 0.73 | SIRT1 (0.56) | MAPKAPK2SIRT1MAPTALDH1A1HTR2B | |
| SCHEMBL8041738 | 0.73 | MAPKAPK2 (0.54) | MAPKAPK2SIRT1MAPTALDH1A1HTR2B | |
| SCHEMBL30363189 | 0.72 | MAPKAPK2 (0.56) | MAPKAPK2SIRT1MAPTALDH1A1HTR2B | |
| SCHEMBL30363250 | 0.72 | MAPKAPK2 (0.56) | MAPKAPK2SIRT1MAPTALDH1A1HTR2B | |
| SCHEMBL30363083 | 0.71 | MAPKAPK2 (0.55) | MAPKAPK2SIRT1MAPTALDH1A1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210179605-A1 | Discovery of Novel First in Class Nature-Inspired Compounds Targeting the Mitochondrial Function and Pharmaceutical Composition Thereof | UNIVERSITY OF SHARJAH (AE) | 2021-06-17 | — | — | US | disclosed |
| WO-2020021489-A2 | DISCOVERY OF NOVEL FIRST IN CLASS NATURE-INSPIRED COMPOUNDS TARGETING THE MITOCHONDRIAL FUNCTION AND PHARMACEUTICAL COMPOSITION THEREOF | UNIVERSITY OF SHARJAH (AE) | 2020-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210179605-A1 | Discovery of Novel First in Class Nature-Inspired Compounds Targeting the Mitochondrial Function and Pharmaceutical Composition Thereof | NDUFAB1, TFAM, CS | MAPKAPK2 2630/4885SIRT1 710/4885MAPT 3368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.