Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 4/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 4/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17807764 | 0.85 | PTPN1 (0.40) | GRM4TBK1KIF11IKBKELMNA | |
| SCHEMBL10216187 | 0.81 | CHRNB2 (0.41) | GRM4TBK1KIF11IKBKELMNA | |
| SCHEMBL12589310 | 0.81 | GRM4 (0.42) | GRM4LMNAALDH1A1KDM4EMAPT | |
| SCHEMBL23478674 | 0.80 | TBK1 (0.36) | TBK1KIF11IKBKELMNAALDH1A1 | |
| SCHEMBL18687390 | 0.80 | TRPA1 (0.40) | TBK1KIF11IKBKELMNAALDH1A1 | |
| SCHEMBL28078490 | 0.80 | GRM4 (0.41) | GRM4LMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL12589297 | 0.80 | GRM4 (0.41) | GRM4 | |
| SCHEMBL12589320 | 0.80 | ESR1 (0.53) | LMNAALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL12546215 | 0.80 | TBK1 (0.45) | TBK1KIF11IKBKELMNAALDH1A1 | |
| SCHEMBL12589280 | 0.80 | KMT2A (0.46) | GRM4LMNAALDH1A1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230373934-A1 | ANDROGEN RECEPTOR MODULATORS AND METHODS FOR THEIR USE | ESSA PHARMA INC. (CA) | 2023-11-23 | — | — | US | disclosed |
| EP-3601231-B1 | PESTICIDAL COMPOUNDS | BASF SE (DE) | 2023-05-10 | — | — | EP | disclosed |
| US-11160280-B2 | Pesticial compounds | BASF SE (DE) | 2021-11-02 | — | — | US | disclosed |
| US-20200029566-A1 | Pesticial Compounds | BASF SE (DE) | 2020-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11160280-B2 | Pesticial compounds | PNMT, DDT, NIT2 | GRM4 3044/4885TBK1 1867/4885KIF11 2124/4885 |
| US-20230373934-A1 | ANDROGEN RECEPTOR MODULATORS AND METHODS FOR THEIR USE | AR, SHBG, NR5A1 | GRM4 398/4885TBK1 4416/4885KIF11 2767/4885 |
| US-20200029566-A1 | Pesticial Compounds | PNMT, DDT, NIT2 | GRM4 3044/4885TBK1 1867/4885KIF11 2124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.