Sugi Predict

Sugi Predict / Compounds / SCHEMBL2164986

SCHEMBL2164986

SCHEMBL2164986

ON=Cc1cc(Cl)cc(Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTT P42858 3/20 0.43
▸ TSHR P16473 2/20 0.42
▸ ALDH1A1 P00352 5/20 0.42
▸ AHR P35869 1/20 0.41
▸ KDM4E B2RXH2 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ CYP1A2 P05177 2/20 0.40
▸ CYP3A4 P08684 2/20 0.40
▸ CYP2C19 P33261 2/20 0.40
▸ PKM P14618 1/20 0.40
▸ CHRM5 P08912 1/20 0.38
▸ KMT2A Q03164 4/20 0.38
▸ MEN1 O00255 3/20 0.38
▸ MAPT P10636 2/20 0.38
▸ HPGD P15428 2/20 0.38
▸ ACHE P22303 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.37
▸ LMNA P02545 2/20 0.36
▸ NPC1 O15118 1/20 0.36
▸ NFKB1 P19838 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2164984 1.00 HTT (0.43) HTTTSHRALDH1A1AHRKDM4E
SCHEMBL10889879 1.00 HTT (0.43) HTTTSHRALDH1A1AHRKDM4E
SCHEMBL2165367 0.84 HTT (0.37) HTTALDH1A1KDM4EL3MBTL1CYP1A2
SCHEMBL2443599 0.84 HTT (0.41) HTTTSHRALDH1A1KDM4EL3MBTL1
SCHEMBL2165369 0.84 HTT (0.37) HTTALDH1A1KDM4EL3MBTL1CYP1A2
SCHEMBL2443595 0.84 HTT (0.41) HTTTSHRALDH1A1KDM4EL3MBTL1
SCHEMBL28618775 0.80 HTT (0.52) HTTALDH1A1KDM4EL3MBTL1CYP1A2
SCHEMBL2444954 0.80 ALDH1A1 (0.45) HTTALDH1A1AHRKDM4EL3MBTL1
SCHEMBL2444956 0.80 ALDH1A1 (0.45) HTTALDH1A1AHRKDM4EL3MBTL1
SCHEMBL758335 0.77 CHRM5 (0.69) ALDH1A1KDM4EL3MBTL1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630499-B2 Benzaldehyde oximes and method for producing same BAYER AKTIENGESELLSCHAFT (DE) 2026-05-19 — — US disclosed
CN-119431264-A 3-Phenyl isoxazoline-5-formamide oxime ester compound and application thereof 沈阳万菱生物技术有限公司 2025-02-14 — — CN disclosed
US-20230348366-A1 BENZALDEHYDE OXIMES AND METHOD FOR PRODUCING SAME BAYER AKTIENGESELLSCHAFT (DE) 2023-11-02 — — US disclosed
EP-4222140-A1 BENZALDEHYDE OXIMES AND METHOD FOR PRODUCING SAME Bayer Aktiengesellschaft (DE) 2023-08-09 — — EP disclosed
CN-116438159-A Benzaldehyde oxime and preparation method thereof 拜耳公司 2023-07-14 — — CN disclosed
EP-2900645-B1 HERBICIDAL AND FUNGICIDAL 3-PHENYLISOXAZOLIN DERIVATIVES BAYER CROPSCIENCE AG (DE) 2019-08-21 — — EP disclosed
US-9585392-B2 3-phenylisoxazolin derivatives with herbicidal action BAYER CROPSCIENCE AG (DE) 2017-03-07 — — US disclosed
US-9516880-B2 Herbicidal and fungicidal 5-oxy-substituted 3-phenylisoxazoline-5-carboxamides and 5-oxy-substituted 3-phenylisoxazoline-5-thioamides BAYER CROPSCIENCE AG (DE) 2016-12-13 — — US disclosed
CN-103596936-B Herbicidal and fungicidal 3-phenylisoxazoline-5-carboxamides and 3-phenylisoxazoline-5-thioamides 拜耳知识产权股份有限公司 2016-11-09 — — CN disclosed
EP-2691379-B1 HERBICIDALLY AND FUNGICIDALLY ACTIVE 3-PHENYLISOXAZOLINE-5-CARBOXAMIDES AND 3-PHENYLISOXAZOLINE-5-THIOAMIDES BAYER IP GMBH (DE) 2016-11-02 — — EP disclosed
WO-2012130798-A1 HERBICIDALLY AND FUNGICIDALLY ACTIVE 3-PHNEYLISOXAZOLINE-5-CARBOXAMIDES AND 3-PHNEYLISOXAZOLINE-5-THIOAMIDES BAYER CROPSCIENCE AG (DE) 2012-10-04 — — WO disclosed
EP-1917269-B1 INHIBITORS OF SERINE PROTEASES VERTEX PHARMA (US) 2011-10-26 — — EP disclosed
EP-2366704-A1 Inhibitors of serine proteases VERTEX PHARMACEUTICALS INCORPORATED (US) 2011-09-21 — — EP disclosed
EP-2364984-A1 Inhibitors of serine proteases VERTEX PHARMACEUTICALS INCORPORATED (US) 2011-09-14 — — EP disclosed
US-7985762-B2 Inhibitors of serine proteases VERTEX PHARMACEUTICALS INCORPORATED (US) 2011-07-26 — — US disclosed
US-20110165120-A1 INHIBITORS OF SERINE PROTEASES VERTEX PHARMACEUTICALS INCORPORATED (US) 2011-07-07 — — US disclosed
US-20070179167-A1 Inhibitors of serine proteases VERTEX PHARMACEUTICALS INCORPORATED 2007-08-02 — — US disclosed
EP-0112524-B1 TRICHLOROACRYLOYL OXIME DERIVATIVES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1986-05-28 — — EP disclosed
US-4581365-A Trichloroacryloyl oxime fungicides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1986-04-08 — — US disclosed
EP-0112524-A1 Trichloroacryloyl oxime derivatives NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1984-07-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348366-A1 BENZALDEHYDE OXIMES AND METHOD FOR PRODUCING SAME AOX1, BBOX1, ALDH7A1 HTT 3379/4885TSHR 2175/4885ALDH1A1 14/4885
US-20110165120-A1 INHIBITORS OF SERINE PROTEASES PRSS1, PRSS3, PRSS2 HTT 3023/4885TSHR 4684/4885ALDH1A1 1374/4885
US-12630499-B2 Benzaldehyde oximes and method for producing same CBR1, CYP2E1, CBR3 HTT 4580/4885TSHR 1330/4885ALDH1A1 36/4885
US-20070179167-A1 Inhibitors of serine proteases PRSS1, PRSS3, PRSS2 HTT 3023/4885TSHR 4684/4885ALDH1A1 1374/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.