Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21652219 | 0.86 | HDAC8 (0.49) | HDAC8NR1H4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL21652257 | 0.82 | NR1H4 (0.65) | NR1H4SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL21620298 | 0.81 | HSD17B1 (0.71) | HSD17B1HSD17B2NPC1 | |
| SCHEMBL12311615 | 0.78 | KMT2A (0.64) | SMN1; SMN2NPC1RAB9APOLBNR1H3 | |
| SCHEMBL13547893 | 0.77 | HDAC8 (0.45) | HDAC8SMN1; SMN2RAB9AALDH1A1RXRA | |
| SCHEMBL21652177 | 0.75 | NR1H4 (0.68) | HDAC8NR1H4NPC1RAB9ANR1H3 | |
| SCHEMBL4876976 | 0.74 | NR1H4 (0.49) | HDAC8HSD17B1HSD17B2NR1H4NPC1 | |
| SCHEMBL12544171 | 0.74 | NR1H3 (0.57) | HDAC8HSD17B1HSD17B2SMN1; SMN2NR1H3 | |
| SCHEMBL7368760 | 0.74 | HTR3E (0.54) | HSD17B1HSD17B2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5415534 | 0.73 | CA1 (0.58) | HSD17B1HSD17B2NR1H4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2020-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | ME1, MAL2, ME3 | HDAC8 2185/4885HSD17B1 1084/4885HSD17B2 1351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.