Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 9/20 | 0.54 |
| ▸ | HSD17B1 | P14061 | 8/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21652226 | 0.89 | HSD17B2 (0.53) | HSD17B2HSD17B1TP53MEN1KMT2A | |
| SCHEMBL11600210 | 0.89 | HSD17B2 (0.53) | HSD17B2HSD17B1TP53MEN1KMT2A | |
| SCHEMBL21620308 | 0.85 | HSD17B2 (0.65) | HSD17B2HSD17B1TP53ALDH1A1HTT | |
| SCHEMBL21620317 | 0.79 | HSD17B2 (0.59) | HSD17B2HSD17B1MEN1KMT2AHTT | |
| SCHEMBL21652269 | 0.79 | HSD17B2 (0.46) | HSD17B2HSD17B1 | |
| SCHEMBL21652177 | 0.77 | NR1H4 (0.68) | NR1H4MEN1RAB9AKMT2ANPSR1 | |
| SCHEMBL6785538 | 0.76 | RXRA (0.45) | HSD17B2HSD17B1MEN1KMT2AALDH1A1 | |
| SCHEMBL4876976 | 0.75 | NR1H4 (0.49) | HSD17B2HSD17B1NR1H4MEN1RAB9A | |
| SCHEMBL14518798 | 0.75 | RXRA (0.44) | HSD17B2HSD17B1MEN1KMT2AALDH1A1 | |
| SCHEMBL21652225 | 0.75 | KCNK9 (0.68) | NR1H4TP53MEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2020-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | ME1, MAL2, ME3 | HSD17B2 1351/4885HSD17B1 1084/4885NR1H4 2555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.