Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23308051 | 0.85 | TSHR (0.38) | TSHRALOX15TAAR1KDM4EAOC3 | |
| SCHEMBL7027684 | 0.80 | L3MBTL1 (0.41) | CNR1TSHRALDH1A1ALOX15HDAC1 | |
| SCHEMBL7027577 | 0.79 | SIGMAR1 (0.42) | CNR1TSHRALDH1A1HDAC1HDAC6 | |
| SCHEMBL169805 | 0.77 | ALDH1A1 (0.47) | CNR1TSHRALDH1A1ALOX15HDAC1 | |
| SCHEMBL14524153 | 0.75 | TSHR (0.50) | TSHRALDH1A1ALOX15APP | |
| SCHEMBL19960650 | 0.75 | ALDH1A1 (0.43) | TSHRALDH1A1HDAC1HDAC6NOS1 | |
| SCHEMBL755823 | 0.75 | RAB9A (0.50) | TSHRALDH1A1ALOX15KMT2ATAAR1 | |
| SCHEMBL10204846 | 0.74 | TAAR1 (0.55) | ALDH1A1TAAR1CYP2D6 | |
| SCHEMBL10356301 | 0.74 | LPL (0.46) | CNR1TSHRALDH1A1ALOX15HDAC1 | |
| SCHEMBL6802392 | 0.73 | KMT2A (0.41) | CNR1TSHRALDH1A1ALOX15HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020023813-A1 | PYRROLO[2,3-B]PYRIDIN DERIVATIVES AS INHIBITORS OF INFLUENZA VIRUS REPLICATION | COCRYSTAL PHARMA, INC. (US) | 2020-01-30 | — | — | WO | disclosed |