Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21662244 | 0.85 | ALDH1A1 (0.37) | ALDH1A1MAPK1LMNAKIF11CFTR | |
| SCHEMBL21661979 | 0.79 | ALDH1A1 (0.33) | ALDH1A1MAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL21662332 | 0.78 | L3MBTL1 (0.36) | ALDH1A1MAPK1KIF11SMN1; SMN2MEN1 | |
| SCHEMBL21662334 | 0.77 | ALDH1A1 (0.40) | ALDH1A1MAPK1LMNACFTRGOPC | |
| SCHEMBL19781085 | 0.76 | MAP1LC3B (0.44) | ALDH1A1MAPK1LMNASMN1; SMN2MEN1 | |
| SCHEMBL21662246 | 0.76 | ALDH1A1 (0.39) | ALDH1A1MAPK1LMNASMN1; SMN2MEN1 | |
| SCHEMBL21662151 | 0.76 | ALDH1A1 (0.39) | ALDH1A1MAPK1LMNACFTRGOPC | |
| SCHEMBL21661975 | 0.73 | L3MBTL1 (0.42) | ALDH1A1L3MBTL1ATMTDP1 | |
| SCHEMBL21662330 | 0.72 | MAP1LC3B (0.35) | ALDH1A1MAPK1LMNASMN1; SMN2MEN1 | |
| SCHEMBL21662147 | 0.72 | L3MBTL1 (0.36) | ALDH1A1MAPK1LMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601257-B1 | AROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2021-10-27 | — | — | EP | disclosed |
| US-20200039903-A1 | AROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200039903-A1 | AROMATIC COMPOUNDS | PAH, ALG3, DDC | ALDH1A1 666/4885MAPK1 4452/4885LMNA 3645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.