SCHEMBL21667296

SCHEMBL21667296

CCc1ccc([Si](C)(C)O[Si](C)(C)C)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.37
TAAR1 Q96RJ0 1/20 0.37
CYP2A6 P11509 1/20 0.35
LPL P06858 1/20 0.35
LIPG Q9Y5X9 1/20 0.35
TDP1 Q9NUW8 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
ALDH1A1 P00352 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
CA2 P00918 1/20 0.33
NOTUM Q6P988 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
ATM Q13315 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
CYP2C19 P33261 1/20 0.32
METAP2 P50579 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3482479 0.80 TP53 (0.39) TP53TAAR1CYP2A6LPLLIPG
SCHEMBL3482171 0.78 TP53 (0.37) TP53TAAR1CYP2A6LPLLIPG
SCHEMBL3482299 0.75 TP53 (0.34) TP53TAAR1CYP2A6LPLLIPG
SCHEMBL21969645 0.75 PLAU (0.32) TP53TAAR1CYP2A6LPLLIPG
SCHEMBL13086261 0.75 ACHE (0.40) TDP1ALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL8306401 0.74 TP53 (0.46) TP53TAAR1CYP2A6LPLLIPG
SCHEMBL13480710 0.74 TP53 (0.46) TP53TAAR1CYP2A6LPLLIPG
SCHEMBL8099751 0.73
SCHEMBL6746677 0.72 LPL (0.35) TP53TAAR1CYP2A6LPLLIPG
SCHEMBL12799192 0.72 AR (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200040119-A1 BLOCK COPOLYMER AND PREPARATION METHOD AND APPLICATION THEREOF FUDAN UNIVERSITY (CN) 2020-02-06 US disclosed