SCHEMBL21667465

SCHEMBL21667465

c1ccc(-c2nc3cccc(-c4ccc(-c5ccccc5)c5ccccc45)c3nc2-c2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
L3MBTL1 Q9Y468 4/20 0.47
KDM4E B2RXH2 5/20 0.44
LMNA P02545 5/20 0.44
GAA P10253 3/20 0.44
ALDH1A1 P00352 3/20 0.44
TDP1 Q9NUW8 2/20 0.43
ADORA2A P29274 2/20 0.42
NUDT1 P36639 1/20 0.42
CYP1A2 P05177 1/20 0.41
DHODH Q02127 2/20 0.41
PDE10A Q9Y233 2/20 0.41
PKM P14618 1/20 0.41
CYP3A4 P08684 1/20 0.40
CYP2C8 P10632 1/20 0.40
CYP2C9 P11712 1/20 0.40
METAP2 P50579 1/20 0.40
TNF P01375 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5987759 0.88 KMT2A (0.56) MEN1KMT2AL3MBTL1KDM4ELMNA
SCHEMBL12202413 0.84 MEN1 (0.42) MEN1KMT2AL3MBTL1KDM4ELMNA
SCHEMBL23385206 0.83 MEN1 (0.44) MEN1KMT2AL3MBTL1KDM4ELMNA
SCHEMBL24266619 0.82 MEN1 (0.40) MEN1KMT2AL3MBTL1KDM4ELMNA
SCHEMBL13078976 0.81 ALDH1A1 (0.45) MEN1KMT2AL3MBTL1KDM4EALDH1A1
SCHEMBL4943241 0.81 ALDH1A1 (0.47) MEN1KMT2AL3MBTL1KDM4EALDH1A1
SCHEMBL23759265 0.80 MEN1 (0.43) MEN1KMT2AL3MBTL1KDM4ELMNA
SCHEMBL24422391 0.80 KMT2A (0.49) MEN1KMT2AL3MBTL1KDM4ELMNA
SCHEMBL28686963 0.80 L3MBTL1 (0.70) MEN1KMT2AL3MBTL1KDM4ELMNA
SCHEMBL12207319 0.80 MEN1 (0.41) MEN1KMT2AL3MBTL1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220052271-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2022-02-17 US disclosed
US-20210359216-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2021-11-18 US disclosed
US-20210305519-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-09-30 US disclosed
US-20210296595-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2021-09-23 US disclosed
US-20200212310-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2020-07-02 US disclosed
WO-2020027444-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2020-02-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212310-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME SOD1, TRPA1, LPO MEN1 4570/4885KMT2A 3396/4885L3MBTL1 23/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.