Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.40 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.38 |
| ▸ | CDK1 | P06493 | 2/20 | 0.38 |
| ▸ | CDK4 | P11802 | 2/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.38 |
| ▸ | CCND1 | P24385 | 2/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11039433 | 0.82 | ALDH1A1 (0.44) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL18345932 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL18345930 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL18345531 | 0.78 | XDH (0.48) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL14989926 | 0.78 | XDH (0.48) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL18346049 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL2487812 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL6904240 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KDM4E | |
| SCHEMBL21631073 | 0.75 | ALDH1A1 (0.39) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL3920843 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TRPA1LMNAALOX5MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3313837-B1 | CARBOLINE ANTIPARASITICS | ZOETIS SERVICES LLC (US) | 2020-09-09 | — | — | EP | disclosed |
| US-10570129-B2 | Carboline antiparasitics | ZOETIS SERVICES LLC (US) | 2020-02-25 | — | — | US | disclosed |
| US-20200031822-A1 | CARBOLINE ANTIPARASITICS | ZOETIS SERVICES LLC (US) | 2020-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10570129-B2 | Carboline antiparasitics | ADRA1D, DRD1, CHRM1 | ALDH1A1 381/4885TRPA1 2577/4885LMNA 2992/4885 |
| US-20200031822-A1 | CARBOLINE ANTIPARASITICS | DRD1, ADRA1D, DRD2 | ALDH1A1 334/4885TRPA1 2709/4885LMNA 3352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.