SCHEMBL2167688

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2170675	0.90	L3MBTL1 (0.52)	L3MBTL1NPC1RAB9AMAPTKMT2A
	SCHEMBL4425283	0.89	MAPT (0.48)	L3MBTL1NPC1RAB9AMAPTKMT2A
	SCHEMBL4414134	0.86	ALDH1A1 (0.49)	L3MBTL1NPC1RAB9AMAPTKMT2A
	SCHEMBL4412368	0.86	MAPT (0.53)	L3MBTL1NPC1RAB9AMAPTKMT2A
	SCHEMBL4415853	0.86	FAAH (0.48)	L3MBTL1NPC1RAB9AMAPTKMT2A
	SCHEMBL4413542	0.86	MCHR1 (0.55)	L3MBTL1NPC1RAB9AMAPTKMT2A
	SCHEMBL4412000	0.86	ABL1 (0.52)	L3MBTL1NPC1RAB9AMAPTKMT2A
	SCHEMBL4417594	0.85	L3MBTL1 (0.48)	L3MBTL1NPC1RAB9AMAPTKMT2A
	SCHEMBL4417580	0.85	HTT (0.52)	L3MBTL1NPC1RAB9AMAPTKMT2A
	SCHEMBL2180733	0.85	NPC1 (0.50)	L3MBTL1NPC1RAB9AMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.