SCHEMBL21679451

SCHEMBL21679451

COc1ccc2cc(C(=O)C#Cc3ccc(C)cc3)ccc2c1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.58
VCP P55072 1/20 0.54
KDM4E B2RXH2 1/20 0.53
ALDH1A1 P00352 1/20 0.49
CYP1A2 P05177 1/20 0.49
HPGD P15428 1/20 0.49
CYP2C19 P33261 1/20 0.49
HSD17B10 Q99714 1/20 0.49
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
LMNA P02545 1/20 0.43
AHR P35869 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
PLAU P00749 1/20 0.43
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
EGFR P00533 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29869041 1.00 APP (0.58) APPVCPKDM4EALDH1A1CYP1A2
SCHEMBL27167232 0.87 APP (0.75) APPVCPNPC1RAB9AMAOA
SCHEMBL28695966 0.87 APP (0.75) APPVCPNPC1RAB9AMAOA
SCHEMBL13344634 0.82 KDM4E (0.51) APPKDM4EALDH1A1CYP1A2HPGD
SCHEMBL10069794 0.80 APP (0.84) APPVCPNPC1RAB9AMEN1
SCHEMBL28972932 0.80 APP (0.64) APPVCPNPC1RAB9AMEN1
SCHEMBL25749196 0.78 VCP (0.82) APPVCPALDH1A1MEN1KMT2A
SCHEMBL16351502 0.77 KDM4E (0.64) KDM4EALDH1A1CYP1A2HPGDCYP2C19
SCHEMBL12847257 0.77 POLB (0.59) KDM4EALDH1A1CYP1A2HPGDCYP2C19
SCHEMBL9745451 0.77 ACHE (0.50) APPKDM4ECYP1A2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109843853-B Composition and method for manufacturing device using the same 东洋合成工业株式会社 2022-09-20 CN disclosed
US-11142495-B2 Composition and method for manufacturing device using same TOYO GOSEI CO., LTD. (JP) 2021-10-12 US disclosed
US-11142495-B2 Composition and method for manufacturing device using same TOYO GOSEI CO., LTD. (JP) 2021-10-12 US disclosed
US-20200048191-A1 COMPOSITION AND METHOD FOR MANUFACTURING DEVICE USING SAME TOYO GOSEI CO., LTD. (JP) 2020-02-13 US disclosed
US-20200048191-A1 COMPOSITION AND METHOD FOR MANUFACTURING DEVICE USING SAME TOYO GOSEI CO., LTD. (JP) 2020-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200048191-A1 COMPOSITION AND METHOD FOR MANUFACTURING DEVICE USING SAME LBR, LMTK2, MMS19 APP 3886/4885VCP 1803/4885KDM4E 2405/4885
US-11142495-B2 Composition and method for manufacturing device using same LBR, LMTK2, MMS19 APP 3886/4885VCP 1803/4885KDM4E 2405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.