SCHEMBL2168495

SCHEMBL2168495

C=Cc1ccc([Si](CC)(CC)OC)cc1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
CHRNB2 P17787 1/20 0.38
CHRNB4 P30926 1/20 0.38
CHRNA3 P32297 1/20 0.38
CHRNA7 P36544 1/20 0.38
CHRNA4 P43681 1/20 0.38
TRPA1 O75762 1/20 0.34
TSHR P16473 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
TAS1R3 Q7RTX0 2/20 0.32
TAS1R1 Q7RTX1 2/20 0.32
TDP1 Q9NUW8 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23071616 0.85 ALDH1A1 (0.39) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL29364686 0.84 CYP1A2 (0.38) ALDH1A1TRPA1TSHR
SCHEMBL710831 0.83 ESR1 (0.37)
SCHEMBL2168264 0.83 ALDH1A1 (0.41) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL2240468 0.81 ALDH1A1 (0.42) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL2354943 0.77 ALDH1A1 (0.52) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL5012806 0.75 ALDH1A1 (0.50) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL27813923 0.75 ALDH1A1 (0.50) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL5014438 0.75 ALDH1A1 (0.50) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL100085 0.75 ALDH1A1 (0.50) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113831478-B ABS resin containing DPE derivative, butadiene, isoprene and styrene star copolymer block and preparation method thereof 大连理工大学 2023-04-28 CN disclosed
CN-113980215-B HIPS resin containing DPE derivative, butadiene, isoprene and styrene star copolymer block and preparation method thereof 大连理工大学 2023-04-28 CN disclosed
CN-113999355-B HIPS resin containing DPE derivative, butadiene and styrene star copolymer blocks and preparation method thereof 大连理工大学 2023-04-28 CN disclosed
CN-113980214-B ABS resin containing DPE derivative, butadiene and styrene star copolymer block and preparation method thereof 大连理工大学 2023-04-28 CN disclosed
CN-113912798-B Star block copolymer based on DPE derivatives, butadiene, isoprene and styrene monomers and preparation method thereof 大连理工大学 2023-03-24 CN disclosed
CN-113999355-A HIPS resin containing DPE derivative, butadiene and styrene star copolymer block and preparation method thereof 大连理工大学 2022-02-01 CN disclosed
CN-113980215-A HIPS resin containing DPE derivative, butadiene, isoprene and styrene star copolymer block and preparation method thereof 大连理工大学 2022-01-28 CN disclosed
CN-113980214-A ABS resin containing DPE derivative, butadiene and styrene star copolymer block and preparation method thereof 大连理工大学 2022-01-28 CN disclosed
CN-113912797-A DPE derivative, butadiene and styrene star block copolymer and preparation method thereof 大连理工大学 2022-01-11 CN disclosed
CN-113912798-A Star block copolymer based on DPE derivatives, butadiene, isoprene and styrene monomers and preparation method thereof 大连理工大学 2022-01-11 CN disclosed
CN-113831478-A ABS resin containing DPE derivative, butadiene, isoprene and styrene star copolymer block and preparation method thereof 大连理工大学 2021-12-24 CN disclosed
CN-113307912-A Silica functionalized SIBR (silicon-oxygen-functionalized-polymer-based elastomer) integrated rubber with star-shaped coupling structure and preparation method thereof 大连理工大学 2021-08-27 CN disclosed
CN-108513626-B Dispersion, coating liquid, and heat-ray shielding film 住友大阪水泥株式会社 2020-05-19 CN disclosed
CN-105579123-B Inorganic particle dispersion, inorganic particle-containing composition, coating film, plastic substrate with coating film, and display device 住友大阪水泥股份有限公司 2020-03-13 CN disclosed
US-10472488-B2 Transparent resin composition and heat ray-shielding film SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2019-11-12 US disclosed
US-20180057655-A1 TRANSPARENT RESIN COMPOSITION AND HEAT RAY-SHIELDING FILM SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2018-03-01 US disclosed
EP-1950239-B1 TRANSPARENT INORGANIC-OXIDE DISPERSION, RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES, COMPOSITION FOR ENCAPSULATING LUMINESCENT ELEMENT, LUMINESCENT ELEMENT, HARD COAT, OPTICAL FUNCTIONAL FILM, OPTICAL PART, AND PROCESS FOR PRODUCING RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES SUMITOMO OSAKA CEMENT CO LTD (JP) 2017-01-04 EP disclosed
US-7985476-B2 Transparent zirconia dispersion and zirconia particle-containing resin composition, composition for sealing light emitting element and light emitting element, hard coat film and optical functional film and optical component, and method for producing zirconia particle-containing resin SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2011-07-26 US disclosed
US-20090140284-A1 Transparent Inorganic Oxide Dispersion and Iorganic Oxide Particle-Containing Resin Composition, Composition for Sealing Light Emitting Element and Light Emitting element, Hard Coat Film and Optical Functional Film and Optical Component, and Method for Producing Inorganic Oxide Pariticle-Containing Resin SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2009-06-04 US disclosed
EP-1950239-A1 TRANSPARENT INORGANIC-OXIDE DISPERSION, RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES, COMPOSITION FOR ENCAPSULATING LUMINESCENT ELEMENT, LUMINESCENT ELEMENT, HARD COAT, OPTICAL FUNCTIONAL FILM, OPTICAL PART, AND PROCESS FOR PRODUCING RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2008-07-30 EP disclosed