SCHEMBL5014438

SCHEMBL5014438

C=Cc1ccc([Si](OC)(OC)c2ccc(C=C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
TSHR P16473 1/20 0.39
TRPA1 O75762 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
TDP1 Q9NUW8 2/20 0.34
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA7 P36544 1/20 0.34
CHRNA4 P43681 1/20 0.34
TP53 P04637 1/20 0.31
TAS1R3 Q7RTX0 1/20 0.31
TAS1R1 Q7RTX1 1/20 0.31
DAPK3 O43293 1/20 0.31
JAK2 O60674 1/20 0.31
ABL1 P00519 1/20 0.31
NTRK1 P04629 1/20 0.31
FYN P06241 1/20 0.31
CSF1R P07333 1/20 0.31
RET P07949 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5146345 0.92 ALDH1A1 (0.48) ALDH1A1TSHRTRPA1HDAC8TDP1
SCHEMBL20872887 0.87 ALDH1A1 (0.43) ALDH1A1TSHRTRPA1TP53DAPK3
SCHEMBL20872939 0.83 NQO2 (0.41) ALDH1A1TSHRTRPA1TDP1CHRNB4
SCHEMBL29895692 0.83 NQO2 (0.41) ALDH1A1TSHRTRPA1TDP1CHRNB4
SCHEMBL100085 0.82 ALDH1A1 (0.50) ALDH1A1TSHRTRPA1HDAC8TDP1
SCHEMBL5012806 0.82 ALDH1A1 (0.50) ALDH1A1TSHRTRPA1HDAC8TDP1
SCHEMBL27813923 0.82 ALDH1A1 (0.50) ALDH1A1TSHRTRPA1HDAC8TDP1
SCHEMBL1448787 0.80 ALDH1A1 (0.48) ALDH1A1TSHRTRPA1HDAC8TDP1
SCHEMBL2770905 0.80 ALDH1A1 (0.48) ALDH1A1TSHRTRPA1HDAC8TDP1
SCHEMBL20873026 0.79 ALDH1A1 (0.38) ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3062134-B1 METHOD FOR MANUFACTURING OPTICAL WAVEGUIDE TOKAI UNIV EDUCATIONAL SYSTEM (JP) 2023-08-02 EP disclosed
EP-3373051-B1 COMPOSITION FOR FORMING OPTICAL WAVEGUIDE NISSAN CHEMICAL CORP (JP) 2020-03-11 EP disclosed
EP-3367144-B1 MANUFACTURING METHOD FOR GI OPTICAL WAVEGUIDE NISSAN CHEMICAL CORP (JP) 2020-03-04 EP disclosed
US-20190338095-A1 PRODUCTION METHOD FOR GI OPTICAL WAVEGUIDE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-11-07 US disclosed
US-10465054-B1 Production method for GI optical waveguide NISSAN CHEMICAL CORPORATION (JP) 2019-11-05 US disclosed
US-10253126-B2 Optical waveguide-forming composition NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-04-09 US disclosed
US-10254649-B2 Method for producing optical waveguide TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) 2019-04-09 US disclosed
US-20180305488-A1 OPTICAL WAVEGUIDE-FORMING COMPOSITION NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-10-25 US disclosed
EP-3373051-A1 COMPOSITION FOR FORMING OPTICAL WAVEGUIDE Nissan Chemical Industries, Ltd. (JP) 2018-09-12 EP disclosed
EP-3367144-A1 MANUFACTURING METHOD FOR GI OPTICAL WAVEGUIDE Nissan Chemical Industries, Ltd. (JP) 2018-08-29 EP disclosed
US-7470761-B2 Proton-conductive membranes and layers and methods for their production FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2008-12-30 US disclosed
EP-1323767-B1 Proton conducting membranes or layers and process for their fabrication FRAUNHOFER GES FORSCHUNG (DE) 2008-03-12 EP disclosed
US-20060058485-A1 Proton-conductive membranes and layers and methods for their production FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. 2006-03-16 US disclosed
US-6984747-B2 Method for preparing styryl-functionalized silanes FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2006-01-10 US disclosed
US-6949616-B2 Proton-conductive membranes and layers and methods for their production FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2005-09-27 US disclosed
EP-1318153-B1 Process for the preparation of styrylsilanes FRAUNHOFER GES FORSCHUNG (DE) 2004-08-04 EP disclosed
US-20030144450-A1 Proton-conductive membranes and layers and methods for their production FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. 2003-07-31 US disclosed
US-20030139621-A1 Method for preparing styryl-functionalized silanes FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. 2003-07-24 US disclosed
EP-1323767-A2 Proton conducting membranes or layers and process for their fabrication Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2003-07-02 EP disclosed
EP-1318153-A1 Process for the preparation of styrylsilanes Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2003-06-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139621-A1 Method for preparing styryl-functionalized silanes SPTSSB, SIRT5, EIF2B2 ALDH1A1 1324/4885TSHR 2430/4885TRPA1 2602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.