Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.35 |
| ▸ | FEN1 | P39748 | 4/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20204677 | 0.84 | PDE2A (0.37) | FFAR4ALOX5APFEN1PDE4DCHUK | |
| SCHEMBL21690528 | 0.81 | RIPK1 (0.38) | FFAR4ALOX5APFEN1PARP15PARP10 | |
| SCHEMBL21325058 | 0.81 | FFAR4 (0.35) | FFAR4ALOX5APFEN1PDE4DCHUK | |
| SCHEMBL21690529 | 0.80 | ALOX5AP (0.34) | FFAR4ALOX5APFEN1PARP15PARP10 | |
| SCHEMBL21534010 | 0.77 | ALOX5AP (0.33) | FFAR4ALOX5APFEN1CHUK | |
| SCHEMBL21534011 | 0.76 | HTR2C (0.36) | FFAR4ALOX5APFEN1PARP15PARP10 | |
| SCHEMBL21325059 | 0.75 | PDE3B (0.35) | FFAR4ALOX5APFEN1PDE4DCHUK | |
| SCHEMBL24180084 | 0.73 | RIPK1 (0.37) | FFAR4ALOX5APFEN1PARP15PARP10 | |
| SCHEMBL21325056 | 0.72 | ALOX5AP (0.34) | FFAR4ALOX5APFEN1 | |
| SCHEMBL20376461 | 0.70 | CYP1A2 (0.38) | ALOX5APFEN1BRD4HTR2CHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11247984-B2 | Uracil containing compounds | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2022-02-15 | — | — | US | disclosed |
| US-20200039966-A1 | URACIL CONTAINING COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200039966-A1 | URACIL CONTAINING COMPOUNDS | UNG, DPYD, DUT | FFAR4 4640/4885ALOX5AP 2695/4885FEN1 21/4885 |
| US-11247984-B2 | Uracil containing compounds | UNG, DPYD, DUT | FFAR4 4640/4885ALOX5AP 2695/4885FEN1 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.