Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | JUN | P05412 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ECE2 | P0DPD6 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108389 | 0.72 | TRPA1 (0.76) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL717976 | 0.72 | TRPA1 (0.76) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL28268121 | 0.64 | CDK4 (0.74) | TRPA1NFKB1CDK4CCND1JUN | |
| Benzene SCHEMBL27382741 | 0.63 | TRPA1 (1.00) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL21684 | 0.63 | TRPA1 (0.61) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL27991 | 0.63 | TRPA1 (1.00) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL30218372 | 0.63 | TRPA1 (1.00) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL27992 | 0.63 | TRPA1 (1.00) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL18109190 | 0.63 | TRPA1 (0.61) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL3464547 | 0.63 | TRPA1 (1.00) | TRPA1NFKB1CDK4CCND1JUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110184072-A1 | FORMULATION INTENDED TO IMPROVING THE BIOAVAILABILITY OF A HYDROPHOBIC MOLECULE | PECHERE LAURENT | 2011-07-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184072-A1 | FORMULATION INTENDED TO IMPROVING THE BIOAVAILABILITY OF A HYDROPHOBIC MOLECULE | FABP2, SI, SLC10A2 | TRPA1 3086/4885NFKB1 411/4885CDK4 3184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.