Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2172676 | 0.80 | CA14 (0.35) | — | |
| SCHEMBL2875764 | 0.79 | ALDH1A1 (0.36) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL17323858 | 0.75 | FAAH (0.35) | ALDH1A1LMNA | |
| SCHEMBL23355839 | 0.72 | DUT (0.31) | — | |
| SCHEMBL16822393 | 0.72 | FAAH (0.41) | ATMLMNAPOLB | |
| SCHEMBL16822394 | 0.72 | FAAH (0.41) | ATMLMNAPOLB | |
| SCHEMBL23355601 | 0.72 | — | — | |
| SCHEMBL1317211 | 0.71 | ADRB2 (0.42) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL16095967 | 0.70 | — | — | |
| SCHEMBL1965746 | 0.70 | SSTR4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346843-A2 | SUBSTITUTED BENZAMIDES AS CANNABINOID RECEPTOR LIGANDS | Abbott Laboratories (US) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010028338-A2 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2010-03-11 | — | — | WO | disclosed |