Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15572905 | 0.89 | CA2 (0.44) | CA2CA1ALDH1A1TDP1TSHR | |
| SCHEMBL21698109 | 0.85 | CA2 (0.40) | CA2CA1ALDH1A1MAPTTDP1 | |
| SCHEMBL1863145 | 0.82 | ALDH1A1 (0.46) | CA2ALDH1A1MAPTTSHRCYP3A4 | |
| SCHEMBL22793524 | 0.78 | TSHR (0.38) | CA2CA1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL23494005 | 0.74 | HCAR2 (0.41) | TAS1R3TAS1R1CHRM1AKR1A1CHRM3 | |
| SCHEMBL8665357 | 0.72 | ACHE (0.46) | CA2ALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL2069188 | 0.72 | ACHE (0.46) | CA2ALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL28113315 | 0.72 | CA2 (0.46) | CA2CA1ALDH1A1TDP1TSHR | |
| SCHEMBL4444563 | 0.70 | CA2 (0.44) | CA2CA1ALDH1A1TDP1TSHR | |
| SCHEMBL16134038 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233881-B1 | UNIVERSAL METHYLATION PROFILING METHODS | UNIV COLUMBIA (US) | 2020-02-12 | — | — | EP | disclosed |