Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15572905 | 0.89 | CA2 (0.44) | CA2CA1TSHRALDH1A1TDP1 | |
| SCHEMBL21698085 | 0.85 | CA2 (0.34) | CA2CA1TSHRALDH1A1TDP1 | |
| SCHEMBL1863145 | 0.76 | ALDH1A1 (0.46) | CA2TSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL22793524 | 0.76 | TSHR (0.38) | CA2CA1TSHRALDH1A1TDP1 | |
| SCHEMBL23494005 | 0.75 | HCAR2 (0.41) | TSHRTDP1CYP3A4TP53ACHE | |
| SCHEMBL7626680 | 0.75 | LMNA (0.48) | ALDH1A1MAPTCYP3A4MEN1FAAH | |
| SCHEMBL18222661 | 0.74 | ACHE (0.37) | TSHRALDH1A1TDP1CYP3A4ACHE | |
| SCHEMBL18222660 | 0.74 | ACHE (0.37) | TSHRALDH1A1TDP1CYP3A4ACHE | |
| SCHEMBL19511360 | 0.73 | ALDH1A1 (0.45) | CA2TSHRALDH1A1TDP1CYP3A4 | |
| SCHEMBL8665357 | 0.73 | ACHE (0.46) | CA2TSHRALDH1A1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233881-B1 | UNIVERSAL METHYLATION PROFILING METHODS | UNIV COLUMBIA (US) | 2020-02-12 | — | — | EP | disclosed |