Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 10/20 | 0.65 |
| ▸ | THRB | P10828 | 10/20 | 0.65 |
| ▸ | THRA | P10827 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16495807 | 0.88 | THRB (0.54) | RORCTHRBTHRAHTT | |
| SCHEMBL282394 | 0.85 | THRB (0.50) | RORCTHRBTHRAHTT | |
| SCHEMBL16496567 | 0.84 | THRB (0.53) | RORCTHRBTHRAHTT | |
| SCHEMBL2169380 | 0.84 | RORC (0.65) | RORCTHRBTHRAHTT | |
| SCHEMBL2169378 | 0.84 | RORC (0.65) | RORCTHRBTHRAHTT | |
| SCHEMBL6818059 | 0.82 | RORC (0.70) | RORCTHRBTHRA | |
| SCHEMBL22959261 | 0.82 | THRB (0.70) | RORCTHRBTHRA | |
| SCHEMBL5619231 | 0.81 | THRB (0.73) | RORCTHRBTHRA | |
| SCHEMBL281885 | 0.80 | THRB (0.79) | RORCTHRBTHRA | |
| SCHEMBL22959356 | 0.80 | RORC (0.67) | RORCTHRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110301200-A1 | THYROID RECEPTOR LIGANDS | CADILA HEALTHCARE LIMITED (IN) | 2011-12-08 | — | — | US | disclosed |
| EP-2346814-A2 | THYROID RECEPTOR LIGANDS | Cadila Healthcare Limited (IN) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010049946-A2 | THYROID RECEPTOR LIGANDS | CADILA HEALTHCARE LIMITED (IN) | 2010-05-06 | — | — | WO | disclosed |
| EP-1148054-B1 | Thyroid receptor ligands | PFIZER PROD INC (US) | 2005-11-23 | — | — | EP | disclosed |
| US-6960604-B2 | Thyroid receptor ligands | PFIZER INC. (US) | 2005-11-01 | — | — | US | disclosed |
| US-20040110951-A1 | Thyroid receptor ligands | CHIANG YUAN-CHING P (US) | 2004-06-10 | — | — | US | disclosed |
| US-6620830-B2 | Certain thiazolidinedione, oxadiazolidinedione, and triazolone compounds which are thyroid receptor ligands | PFIZER, INC. | 2003-09-16 | — | — | US | disclosed |
| US-20010051645-A1 | Thyroid receptor ligands | CHIANG YUAN-CHING P (US) | 2001-12-13 | — | — | US | disclosed |
| EP-1148054-A1 | Thyroid receptor ligands | Pfizer Products Inc. (US) | 2001-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301200-A1 | THYROID RECEPTOR LIGANDS | TSHR, THRB, THRA | RORC 79/4885THRB 2/4885THRA 3/4885 |
| US-20010051645-A1 | Thyroid receptor ligands | TSHR, THRB, THRA | RORC 302/4885THRB 2/4885THRA 3/4885 |
| US-20040110951-A1 | Thyroid receptor ligands | TSHR, THRB, THRA | RORC 302/4885THRB 2/4885THRA 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.