Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 10/20 | 0.70 |
| ▸ | RORC | P51449 | 10/20 | 0.70 |
| ▸ | THRA | P10827 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL281885 | 0.86 | THRB (0.79) | THRBRORCTHRA | |
| SCHEMBL6818059 | 0.86 | RORC (0.70) | THRBRORCTHRA | |
| SCHEMBL22959356 | 0.83 | RORC (0.67) | THRBRORCTHRA | |
| SCHEMBL2169907 | 0.82 | RORC (0.65) | THRBRORCTHRA | |
| SCHEMBL282442 | 0.82 | THRB (1.00) | THRBRORCTHRA | |
| SCHEMBL7069261 | 0.82 | THRB (0.77) | THRBRORCTHRA | |
| SCHEMBL5619231 | 0.81 | THRB (0.73) | THRBRORCTHRA | |
| SCHEMBL23663148 | 0.81 | THRB (0.46) | THRBRORCTHRA | |
| SCHEMBL5327698 | 0.80 | RORC (0.62) | THRBRORCTHRA | |
| SCHEMBL282476 | 0.80 | RORC (0.66) | THRBRORCTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021026179-A1 | AGONISTS OF ROR GAMMAt | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-02-11 | — | — | WO | disclosed |