Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 11/20 | 0.70 |
| ▸ | THRB | P10828 | 10/20 | 0.70 |
| ▸ | THRA | P10827 | 5/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.43 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3221389 | 0.87 | THRB (0.57) | RORCTHRBTHRA | |
| SCHEMBL22959261 | 0.86 | THRB (0.70) | RORCTHRBTHRA | |
| SCHEMBL14264315 | 0.85 | RORC (0.62) | RORCTHRBTHRAP2RX3P2RX2 | |
| SCHEMBL8893247 | 0.84 | THRB (0.57) | RORCTHRBTHRAP2RX3P2RX2 | |
| SCHEMBL282017 | 0.84 | THRB (0.53) | RORCTHRBTHRAP2RX3P2RX2 | |
| SCHEMBL22959356 | 0.83 | RORC (0.67) | RORCTHRBTHRA | |
| SCHEMBL281885 | 0.83 | THRB (0.79) | RORCTHRBTHRA | |
| Hydrochloric Acid SCHEMBL8800518 | 0.83 | THRB (0.52) | RORCTHRBTHRAP2RX3P2RX2 | |
| SCHEMBL7069261 | 0.82 | THRB (0.77) | RORCTHRBTHRA | |
| SCHEMBL282442 | 0.82 | THRB (1.00) | RORCTHRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220306630-A1 | AGONISTS OF ROR GAMMAt | BRISTOL MYERS SQUIBB CO (US) | 2022-09-29 | — | — | US | claimed |
| WO-2021026179-A1 | AGONISTS OF ROR GAMMAt | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-02-11 | — | — | WO | claimed |
| US-20220306630-A1 | AGONISTS OF ROR GAMMAt | BRISTOL MYERS SQUIBB CO (US) | 2022-09-29 | — | — | US | disclosed |
| WO-2021026179-A1 | AGONISTS OF ROR GAMMAt | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-02-11 | — | — | WO | disclosed |
| WO-2021026179-A1 | AGONISTS OF ROR GAMMAt | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-02-11 | — | — | WO | disclosed |
| WO-2004018421-A1 | IDOL DERIVATIVES AS NEW THYROID RECEPTOR AGONIST LIGANDS AND METHODS | KARO BIO AB. (SE) | 2004-03-04 | — | — | WO | disclosed |
| EP-0580550-B1 | Oxamic acid derivatives as hypocholesteremic agents | CIBA GEIGY AG (CH) | 1997-10-22 | — | — | EP | disclosed |
| US-5654468-A | ANTILIPID, ANTICHOLESTEROL AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-08-05 | — | — | US | disclosed |
| US-5569674-A | ANTICHOLESTEROL AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-10-29 | — | — | US | disclosed |
| US-5401772-A | Anticholesterol agents with aromatic amines | CIBA-GEIGY CORPORATION (US) | 1995-03-28 | — | — | US | disclosed |
| EP-0580550-A1 | Oxamic acid derivatives as hypocholesteremic agents | CIBA-GEIGY AG (CH) | 1994-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220306630-A1 | AGONISTS OF ROR GAMMAt | RORB, RORA, RORC | RORC 3/4885THRB 44/4885THRA 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.