Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21699995 | 0.78 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL21670190 | 0.78 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL28618546 | 0.78 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL21699994 | 0.77 | KMT2A (0.37) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL21702675 | 0.75 | MEN1 (0.37) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL21699971 | 0.72 | JAK2 (0.33) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL21699991 | 0.72 | KMT2A (0.39) | ALDH1A1MEN1KMT2ARAB9ASTAT3 | |
| SCHEMBL23762448 | 0.70 | KMT2A (0.33) | ALDH1A1MEN1KMT2A | |
| SCHEMBL28613897 | 0.69 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL28613899 | 0.69 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3608326-A1 | TRICYCLIC INHIBITORS OF HEPATITIS B VIRUS | IRBM S.P.A. (IT) | 2020-02-12 | — | — | EP | disclosed |