Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21700075 | 0.81 | NPC1 (0.47) | MEN1KMT2ALMNAMAPTMAOB | |
| SCHEMBL21670141 | 0.80 | LMNA (0.40) | MEN1KMT2ALMNAMAPTMAOB | |
| SCHEMBL28619403 | 0.80 | LMNA (0.40) | MEN1KMT2ALMNAMAPTMAOB | |
| SCHEMBL29592841 | 0.80 | LMNA (0.40) | MEN1KMT2ALMNAMAPTMAOB | |
| SCHEMBL21699962 | 0.80 | MEN1 (0.38) | MEN1KMT2ALMNAMAPTMAOB | |
| SCHEMBL21700035 | 0.79 | RAB9A (0.46) | MEN1KMT2ALMNAMAPTMAOB | |
| SCHEMBL21700069 | 0.75 | ALDH1A1 (0.31) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21699989 | 0.71 | ENPP2 (0.32) | ENPP2 | |
| SCHEMBL21670242 | 0.71 | ENPP2 (0.37) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL23082190 | 0.71 | RAB9A (0.49) | MEN1KMT2ALMNAMAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020030781-A1 | TRICYCLIC INHIBITORS OF HEPATITIS B VIRUS | OSPEDALE SAN RAFFAELE S.R.L. (IT) | 2020-02-13 | — | — | WO | disclosed |