Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | PPM1B | O75688 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20990681 | 0.81 | DRD2 (0.46) | DRD2DRD3SMN1; SMN2PPM1BPTPN1 | |
| Water SCHEMBL28039499 | 0.74 | TP53 (0.41) | TP53SMN1; SMN2PPM1BPTPN1PPP1CC | |
| SCHEMBL791232 | 0.72 | BRD4 (0.46) | TP53SMN1; SMN2PPM1BPTPN1POLB | |
| SCHEMBL20990709 | 0.71 | MTNR1A (0.46) | DRD2DRD3SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL3879955 | 0.71 | TP53 (0.44) | TP53SMN1; SMN2PPM1BPTPN1PPP1CC | |
| Acetonitrile SCHEMBL28144367 | 0.71 | SMN1; SMN2 (0.55) | TP53SMN1; SMN2PPM1BPTPN1PPP1CC | |
| SCHEMBL244740 | 0.71 | — | — | |
| SCHEMBL2948892 | 0.71 | TP53 (0.56) | TP53SMN1; SMN2PPM1BPTPN1PPP1CC | |
| SCHEMBL2200767 | 0.71 | TP53 (0.56) | TP53SMN1; SMN2PPM1BPTPN1PPP1CC | |
| SCHEMBL74396 | 0.71 | TP53 (0.56) | TP53SMN1; SMN2PPM1BPTPN1PPP1CC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912704-B2 | Methods and compositions for substituted arylcycloheptane analogs | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| US-20210300928-A1 | METHODS AND COMPOSITIONS FOR SUBSTITUTED ARYLCYCLOHEPTANE ANALOGS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2021-09-30 | — | — | US | disclosed |
| WO-2020033567-A1 | METHODS AND COMPOSITIONS FOR SUBSTITUTED ARYLCYCLOHEPTANE ANALOGS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2020-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300928-A1 | METHODS AND COMPOSITIONS FOR SUBSTITUTED ARYLCYCLOHEPTANE ANALOGS | AHR, HCCS, HMBS | DRD2 1498/4885DRD3 1435/4885TP53 2456/4885 |
| US-11912704-B2 | Methods and compositions for substituted arylcycloheptane analogs | AHR, HCCS, HMBS | DRD2 1498/4885DRD3 1435/4885TP53 2456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.