SCHEMBL21705261

SCHEMBL21705261

O=C(OCCN1CCOCC1)c1cccc(I)c1

nearest known ligand 0.72

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.72
GAA P10253 2/20 0.62
ATM Q13315 1/20 0.62
SMN1; SMN2 Q16637 2/20 0.61
KDM4E B2RXH2 2/20 0.56
PKM P14618 1/20 0.56
KMT2A Q03164 2/20 0.55
LMNA P02545 1/20 0.55
ALDH1A1 P00352 6/20 0.52
NPSR1 Q6W5P4 1/20 0.52
HPGD P15428 1/20 0.52
HRH3 Q9Y5N1 1/20 0.48
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
MAPT P10636 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21783765 0.87 NPSR1 (0.67) L3MBTL1KDM4EKMT2AALDH1A1NPSR1
SCHEMBL10084675 0.85 L3MBTL1 (0.97) L3MBTL1GAAATMSMN1; SMN2KDM4E
SCHEMBL28326195 0.85 L3MBTL1 (0.72) L3MBTL1GAAATMSMN1; SMN2KDM4E
SCHEMBL2106336 0.85 L3MBTL1 (0.72) L3MBTL1GAAATMSMN1; SMN2KDM4E
SCHEMBL21705702 0.85 NPSR1 (0.52) L3MBTL1GAAATMSMN1; SMN2KDM4E
SCHEMBL21705258 0.85 NPSR1 (0.52) L3MBTL1GAAATMSMN1; SMN2KDM4E
SCHEMBL21783808 0.85 NPSR1 (0.52) L3MBTL1GAAATMSMN1; SMN2KDM4E
SCHEMBL2821475 0.84 ATM (0.77) L3MBTL1GAAATMSMN1; SMN2KDM4E
SCHEMBL501720 0.84 ATM (0.76) L3MBTL1GAAATMSMN1; SMN2KDM4E
SCHEMBL5350446 0.82 ATM (0.74) L3MBTL1GAAATMSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11835859-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-12-05 US disclosed
US-11774853-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-10-03 US disclosed
US-11774853-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-10-03 US disclosed
US-20230129578-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-04-27 US disclosed
US-20230129578-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-04-27 US disclosed
US-11187980-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-11-30 US disclosed
US-20200192222-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-06-18 US disclosed
US-20200073237-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-03-05 US disclosed
US-20200050105-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200050105-A1 RESIST COMPOSITION AND PATTERNING PROCESS HNRNPU, HNRNPR, ZFR L3MBTL1 1874/4885GAA 4569/4885ATM 3719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.