SCHEMBL21705288

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL26834855	0.86	HTR4 (0.39)	HTR4HDAC1HDAC2HDAC3CHRM3
	SCHEMBL21705229	0.82	HTR4 (0.43)	HTR4HDAC1HDAC2HDAC3CHRM3
	SCHEMBL26426646	0.75	HTR4 (0.49)	HTR4HDAC1HDAC2HDAC3ADRA2C
	SCHEMBL11819470	0.70	ESR1 (0.37)	ADRA1ACYP1A2CYP3A4CYP2C9LMNA
	SCHEMBL21705230	0.69	CHRNB4 (0.55)	HDAC1HDAC2CHRM3CYP2D6
	SCHEMBL28682255	0.67	NCF1 (0.47)	HTR4HDAC1HDAC2HDAC3CHRM3
	SCHEMBL30398594	0.67	HTR4 (1.00)	HTR4ADRA2CHTR1DHTR2BHTR2C
	SCHEMBL30364521	0.67	HTR4 (1.00)	HTR4ADRA2CHTR1DHTR2BHTR2C
	SCHEMBL26807612	0.67	ALDH1A1 (0.37)	ADRA1ACYP1A2CYP2C9LMNA
	SCHEMBL19765231	0.66	NCF1 (0.41)	HTR4HDAC1HDAC2HDAC3CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.