Water

Water

SCHEMBL2170632

O.OC(F)(C(F)F)C(F)(F)F

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL29263408 0.97
SCHEMBL198 0.96
SCHEMBL288066 0.96
SCHEMBL11480259 0.96
SCHEMBL18813405 0.93
Ammonia Solution, Strong SCHEMBL28844129 0.93
Fluoride SCHEMBL28250588 0.93
SCHEMBL27951792 0.93
SCHEMBL27540763 0.93
Ethylene SCHEMBL6705461 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113588851-B Method for extracting and measuring dithiocarbamic acid ester, measuring device and application thereof 福建中烟工业有限责任公司 2023-06-09 CN claimed
CN-113588851-A Method for extracting and determining dithiocarbamate, determination device and application thereof 福建中烟工业有限责任公司 2021-11-02 CN claimed
CN-110105682-A A kind of high performance PP plastics and preparation method thereof 王德秀 2019-08-09 CN claimed
CN-110041631-A A kind of wear-resistant plastic of modification and preparation method thereof 王德秀 2019-07-23 CN claimed
CN-118225940-A Method for determining content of oligonucleotides in biological matrix 北京昭衍新药研究中心股份有限公司 2024-06-21 CN disclosed
CN-113588851-B Method for extracting and measuring dithiocarbamic acid ester, measuring device and application thereof 福建中烟工业有限责任公司 2023-06-09 CN disclosed
CN-113588851-B Method for extracting and measuring dithiocarbamic acid ester, measuring device and application thereof 福建中烟工业有限责任公司 2023-06-09 CN disclosed
CN-115505027-A Fluorescent dipeptide molecule self-assembly and application thereof in circular polarization luminescence 苏州欧德丽尔新材料科技有限公司 2022-12-23 CN disclosed
CN-115436554-A Exposure simulation device and method for plant leaf surface to absorb micro/nano plastic in atmosphere 南开大学 2022-12-06 CN disclosed
CN-113588851-A Method for extracting and determining dithiocarbamate, determination device and application thereof 福建中烟工业有限责任公司 2021-11-02 CN disclosed
CN-113588851-A Method for extracting and determining dithiocarbamate, determination device and application thereof 福建中烟工业有限责任公司 2021-11-02 CN disclosed
CN-110105682-A A kind of high performance PP plastics and preparation method thereof 王德秀 2019-08-09 CN disclosed
CN-110041631-A A kind of wear-resistant plastic of modification and preparation method thereof 王德秀 2019-07-23 CN disclosed
US-9061042-B2 Composition for suppressing expression of target gene KYOWA HAKKO KIRIN CO., LTD. (JP) 2015-06-23 US disclosed
CN-101885847-B Method for preparing organophosphorus sensitive polymer material by introducing hexafluoroisopropanol functional group into polymer UNIV ELECTRONIC SCIENCE & TECH 2012-07-04 CN disclosed
US-20110182980-A1 COMPOSITION FOR SUPPRESSING EXPRESSION OF TARGET GENE KYOWA KIRIN CO., LTD. (JP) 2011-07-28 US disclosed
CN-101885847-A Method for preparing organophosphorus sensitive polymer material by introducing hexafluoroisopropanol functional group into polymer UNIV ELECTRONIC SCIENCE & TECH 2010-11-17 CN disclosed
US-4063090-A Method for isotope separation by photodeflection THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES ENERGY RESEARCH AND DEVELOPMENT ADMINISTRATION (US) 1977-12-13 US disclosed