Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 4/20 | 0.40 |
| ▸ | CTSL | P07711 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.38 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4957420 | 0.72 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL4954832 | 0.71 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL4867352 | 0.71 | CTSS (0.42) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL11248 | 0.70 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL16847835 | 0.70 | CTSK (0.69) | CTSBCTSLCTSSCTSK | |
| SCHEMBL3965574 | 0.70 | GPR88 (0.46) | ALDH1A1GLATSHRCTSBCTSL | |
| SCHEMBL4866152 | 0.70 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL18765958 | 0.70 | ALDH1A1 (0.66) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL11405182 | 0.69 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL17629514 | 0.69 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1CTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973037-B2 | Cathepsin cysteine protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2011-07-05 | — | — | US | disclosed |